Vocal markers from sustained phonation in Huntington's Disease

June 09, 2020 · Entered Twilight · 🏛 Interspeech

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Repo contents: LICENSE, README.md, Sustained_Phonation.ipynb, environment.yml, example_sound, features

Authors Rachid Riad, Hadrien Titeux, Laurie Lemoine, Justine Montillot, Jennifer Hamet Bagnou, Xuan Nga Cao, Emmanuel Dupoux, Anne-Catherine Bachoud-Lévi arXiv ID 2006.05365 Category eess.AS: Audio & Speech Cross-listed cs.CL, cs.SD Citations 18 Venue Interspeech Repository https://github.com/bootphon/sustained-phonation-features ⭐ 12 Last Checked 1 month ago

Abstract

Disease-modifying treatments are currently assessed in neurodegenerative diseases. Huntington's Disease represents a unique opportunity to design automatic sub-clinical markers, even in premanifest gene carriers. We investigated phonatory impairments as potential clinical markers and propose them for both diagnosis and gene carriers follow-up. We used two sets of features: Phonatory features and Modulation Power Spectrum Features. We found that phonation is not sufficient for the identification of sub-clinical disorders of premanifest gene carriers. According to our regression results, Phonatory features are suitable for the predictions of clinical performance in Huntington's Disease.